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NIH experts call for accelerated research to address concurrent HIV and COVID-19 pandemics

NIH News Releases - April 8, 2021 - 6:15pm
The COVID-19 pandemic is affecting people with or at risk for HIV indirectly and direct.

Categories: NIH

National Institute of General Medical Sciences (NIGMS) Bridges to the Doctorate (T32)

Funding Opportunity PAR-21-198 from the NIH Guide for Grants and Contracts. The goal of the Bridges to the Doctorate Research Training program is to develop a diverse pool of scientists earning a Ph.D., who have the skills to successfully transition into careers in the biomedical research workforce. This funding opportunity announcement (FOA) provides support to eligible, domestic institutions to develop and implement effective, evidence-based approaches to biomedical training and mentoring that will keep pace with the rapid evolution of the research enterprise. NIGMS expects that the proposed research training programs will incorporate didactic, research, mentoring, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the Nation. This Funding Opportunity Announcement (FOA) does not allow appointed Trainees to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.
Categories: NIH

NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01 Independent Clinical Trial Not Allowed)

Funding Opportunity PAR-21-152 from the NIH Guide for Grants and Contracts. (Reissue of PAR-18-490) The purpose of the NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01) is to diversify the pool of independent neuroscience research investigators by providing junior faculty with research cost support, protected research time and career stage appropriate professional development mentorship in neuroscience research. Individuals from backgrounds underrepresented in biomedical research are eligible for support under this award if they have doctoral research degrees (Ph.D. or equivalent) and are in the first 3 years of a faculty tenure track or equivalent position at the time of application. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor.
Categories: NIH

NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01 Clinical Trial Required)

Funding Opportunity PAR-21-153 from the NIH Guide for Grants and Contracts. (Reissue of PAR-18-486) The purpose of the NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01) is to diversify the pool of independent neuroscience research investigators by providing junior faculty with research cost support, protected research time and career stage appropriate professional development mentorship in neuroscience research. Individuals from backgrounds underrepresented in biomedical research are eligible for support under this award if they have doctoral research degrees (Ph.D. or equivalent) and are in the first 3 years of a faculty tenure track or equivalent position at the time of application. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary study to an existing trial, as part of their research and career development. NINDS will only accept applications to this FOA that propose human mechanistic trials/studies that meet NIH's definition of a clinical trial and that fall within the NINDS research priorities. Applicants are strongly advised to consult with NINDS program staff prior to submitting an application with human subjects to determine the appropriate funding opportunity.
Categories: NIH

Emergency Award: Social, Behavioral, and Economic Research on COVID-19 Consortium Coordinating Center (U24 Clinical Trial Not Allowed)

Funding Opportunity RFA-AG-21-035 from the NIH Guide for Grants and Contracts. The purpose of this cooperative resource-related research project FOA is to establish a coordinating center to support and develop research, dissemination, and various data sharing activities for social, behavioral, and economic research on COVID-19.
Categories: NIH

NIH-funded research team develops language test for people with Down syndrome

NIH News Releases - April 8, 2021 - 11:30am
Language delays are common in people with Down syndrome.

Categories: NIH

Centers on Telehealth Research for Cancer-Related Care (P50 Clinical Trial Required)

Funding Opportunity RFA-CA-21-029 from the NIH Guide for Grants and Contracts. Informed by stakeholder input and a scan of the existing clinical and research landscape, the purpose of this initiative is to fund three research centers that can advance a national cancer-related telehealth research agenda in a rapidly changing healthcare, policy, and communication environment. Each center will support one signature project: a large pragmatic trial with the potential to generate findings with broad applicability to clinical practice and heterogenous patient populations. This collective of research centers will also support the infrastructure needed for designing innovative pilot studies on emerging issues in telehealth and cancer. The work of these centers is expected to foster the development, evaluation, and dissemination of innovative forms of telehealth with the potential to advance the delivery of cancer-related care as evidenced by improvements in quality of life and clinical outcomes, patient-physician communication, health equity, and/or access to quality care.
Categories: NIH

Leveraging Artificial Intelligence (AI) tools for Substance Use Disorders (SUD) drug discovery and development (R41/R42 - Clinical Trial Not Allowed)

Funding Opportunity RFA-DA-22-021 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits grant applications from small business concerns (SBCs) to develop Artificial Intelligence (AI)-related technologies for drug discovery and drug development for Substance Use Disorders (SUD), excluding alcohol use disorder
Categories: NIH

Leveraging Artificial Intelligence (AI) tools for Substance Use Disorders (SUD) drug discovery and development (R43/R44 - Clinical Trial Not Allowed)

Funding Opportunity RFA-DA-22-019 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits grant applications from small business concerns (SBCs) to develop Artificial Intelligence (AI)-related technologies for drug discovery and drug development for Substance Use Disorders (SUD), excluding alcohol use disorder
Categories: NIH

BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access and Manipulation to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)

Funding Opportunity RFA-MH-21-180 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) from the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is intended to support establishment of facilities at minority-serving institutions (MSIs) and Institutional Development Award (IDeA)-eligible institutions for scaled production and distribution of brain cell type-specific access and manipulation reagents. Reagents will be initially developed in pilot resource projects for brain cell type-specific access and manipulation across vertebrate species from the BRAIN Initiative Armamentarium project. Awardees under this FOA will work with the other Armamentarium awardees to manufacture and distribute the resources for use throughout the neuroscience community. It is envisioned that the awardees will work both with the Armamentarium community as well as with the neuroscience research community to optimize the use of new reagents. The types of reagents to be produced and distributed could include but are not limited to viral vectors, nucleic acid constructs, and nanoparticles designed for selective access to and manipulation of brain cell types. Such reagents will enable neuroscientists to probe circuit function with high precision in experimental animals and ex vivo human tissue and cells. Facilities are needed to contribute to the production and distribution of BRAIN Initiative Armamentarium project reagents broadly to neuroscience users.
Categories: NIH

NIH begins study of allergic reactions to Moderna, Pfizer-BioNTech COVID-19 vaccines

NIH News Releases - April 7, 2021 - 1:30pm
A systemic allergic reaction to a vaccine occurs in one or more parts of the body beyond the injection site.

Categories: NIH

How Are Schools and Departments Assigned to NIH Grants?

NIH Extramural Research & Funding News - April 7, 2021 - 9:26am

For decades, NIH has collected and curated information on the schools and departments associated with the grants awarded to domestic higher education academic institutions to provide statistics on the fields contributing to advances in biomedical research. This information appears in NIH RePORTER (Figure 1), NIH Awards by Location and Organization, and other reports issued by NIH. To facilitate uniform reporting, NIH aligns the schools and department names used by institutions to standard lists of school types and department types.

Figure 1

Signing officials can ensure the accuracy of their institution’s assignment through tools in the eRA Commons (Figure 2). They can also edit this information for awards themselves or request manual corrections through the eRA Service Desk. To help facilitate review by signing officials, we send annual reminders towards the end of each fiscal year, such as this Guide Notice from 2020, reminding our recipients verify the accuracy of the grant assignments.

Figure 2

NIH uses automated procedures to propose a school and department assignment based on information from the SF424 (R&R) grant application. The Division field is used to determine a school or major component (e.g. School of Public Health) and the Department field is used to determine the academic department.

Figure 3

Our systems follow this order of operations when making school and department assignments:

  • Machine-learning approaches using text provided in the application and matched to past assignments by NIH and signing officials
  • Free-text information from the Division field, as matched to schools and other major components of the institution, and similar information from the Department field matched to a suggested department at the institution.
  • For competing continuation grant applications (Type 2), the assignments from an earlier version of the award may be carried forward to the new application if the principal investigator and institution are unchanged.
  • Recent applications and awards from the same principal investigator and institution where the information was available or updated by the signing official.
  • Other information on departments or school names mentioned in address fields.

If no information is available, NIH assigns either “UNIVERSITY WIDE” or “NONE” for the major component or department, respectively. Finally, the specific institution’s schools and departments are rolled up into standard reporting categories of school types and department types.

Categories: NIH

Limited Interaction Targeted Epidemiology (LITE-2): To Advance HIV Prevention (UG3/UH3 Clinical Trial Optional)

Funding Opportunity RFA-AI-21-018 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications that use innovative technology to conduct epidemiologic studies of large cohorts of U.S. populations at high risk of HIV: men who have sex with men (MSM), people who inject drugs (PWID), and transgender women and men, focusing especially on the minority and age groups at highest risk of HIV transmissions. The major goal is to support investigators who will use innovative electronic methods to recruit and retain large samples of persons at high risk of HIV, comparing those who become HIV-positive to those who do not, and optionally to develop and test digitally-delivered interventions that promote HIV risk reduction to reduce HIV-incidence.
Categories: NIH
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