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Biological Age and Its Value for Behavioral and Decision Science

Principal Investigator
Gideon Nave
Aims

This research program aims to break new grounds in our understanding of how biological aspects of aging are associated with individual differences in psychological dispositions, as well as cognitive and emotional aspects of decision-making in humans. To this end, we will rely on recent advances in the field of bioinformatics, and utilize new epigenetic biomarkers called “epigenetic clocks”. We will combine these biomarkers—obtained from the Health and Retirement Study—with individual-level measures of psychological characteristics (including but not limited to personality, impulsivity, risk tolerance, patience, and confidence) collected via surveys and behavioral experiments. To the best of our knowledge, epigenetic clocks have only been utilized to date for understanding health-related outcomes in medical research, but have not been used for understanding how biological aging affects cognition and decision-making.

Abstract

The proposed project draws on recent advances in bio-informational research, with an aim to investigate how a new type of measurement—called “epigenetic clocks”, which quantifies biological processes related to aging (i.e., biological age)—can better our understanding of individuals’ judgments and decisions. At this time, epigenetic clocks have been previously used in medical research to understand the aging process and human lifespan, and such measures have been shown to be better at capturing variability in biological aging processes than chronological age. In this project, we will conduct secondary data analysis using epigenetic clocks data from the Health and Retirement Study to investigate the usefulness of biological age for understanding consumer behavior. Using survey measures combined with epigenetic data, we seek to differentiate the contribution of biological aging from other non-biological aging-related measures (such as chronological age), and empirically disentangle their effects on psychological well-being as well as other meaninful outcomes. Funding from this grant will be used to pay for research assistant time.

Funded By
PARC
Award Dates
July 1, 2022 - June 30, 2023

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The Population Studies Center (PSC) at the University of Pennsylvania (Penn) was founded in 1962 and stands as an international leader in research and training on the dynamic structure, organization, and health and well-being of human populations. The services that PSC provides have been funded by infrastructure grants awarded by the Population Dynamics Branch at Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) since 1978. The center and its associates are also supported by research grants and contracts awarded by federal agencies including the National Institutes of Health and the National Science Foundation and by private foundations. Penn’s School of Arts and Sciences is the administrative home of the PSC and provides generous dedicated support to the center.

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